Born and raised in Austin, Texas, Jake Andrews grew up in a house and city filled with music. He began playing guitar at age 5, taught by his father, John Andrews of the 60's Roots Band Mother Earth. At an early age, Jake began attending shows at the legendary blues venue, Antone's, to see legends like BB King and Albert Collins perform. At age 8, Jake first went onstage to play guitar with Albert King. Impressed with the young guitarist, King invited Jake to play with him for his entire second set. The next day the Austin Chronicle reported that King and Andrews "brought the house down with fine blues playing." That moment sparked Jake's young career, and he continued to hone his skills in the clubs of Austin, Texas regularly performing with local musicians and soaking up the sounds of the music-filled city.

Jake has performed with music giants such as BB King, Buddy Guy, Albert King and Jimmie Vaughan. Jake has also performed at major festivals such as the San Francisco Blues Festival and Madison Blues Festival with Ray Charles. He has been featured on CBS, Austin City Limits with Grey Ghost, Texas Monthly, Guitar Player, and Vintage Guitar among numerous other publications verifying the talent and hard work that Jake has put into his music career. He has toured the US and Europe extensively.

At the age of 17, Jake was signed to Jericho records, a subsidiary of Warner Brothers. In 1999, Jake released his much anticipated debut album 'Time to Burn' with legendary producer John Porter (BB King, Buddy Guy, Los Lonely Boys). The album unleashed a solid assortment of material played and sung with compelling conviction and an electrifying virtuosity that would draw a smile of approval from his illustrious musical mentors. Billboard magazine stated, "Time to Burn's mix of guitar pyrotechnics, fiery vocals and powerful new songs confirms that Jake Andrews is already blazing new paths with the torch he's been passed." The first title single scored a Top Ten Rock Radio hit. Jake earned the award of "Breakout Rock Group" in 1999 by R&R (Radio and Records). The record was supported with a tour with artists including the Allman Brothers, The Doobie Brothers, Susan Tedeschi, and George Thorogood.

Andrews is featured on the solo album by Paul Jones released March 10, 2009. Paul Jones is known to many as the singer of the British Invasion band Manfred Mann — the voice on mid-‘60s hits like “Do Wah Diddy,” “Pretty Flamingo,” “Come Tomorrow” and “Sha La La.” Backing Jones on the project are musicians: Eric Clapton plays guitar on two tracks (“Choose or Cop Out” and “Starting All Over Again”) and is joined by Jake Andrews, guitar; Tony Marsico, bass; Alvino Bennett, drums; Mike Thompson, piano and Hammond B3 organ; Ernie Watts, saxophone; Darrell Leonard, trumpet; Tom Junior Moran, saxophone; Mikael Rickfors, backing vocals; and several others.

In 2006, Andrews joined Guitar Shorty, on his Alligator Release "We the People" accompanying the legendary bluesman on the album. The album won "Album of the Year" at the WC Handy awards in May 2007. Andrews hit the road with Guitar Shorty in the summer and fall of 2006 for a full US and European tour.

In 2002 Jake released a second self-titled album produced by Carla Olson (Phil Upchurch, Joe Louis Walker, Otis Rush, Barry Goldberg, Mick Taylor). The album was recorded at the Willie Nelson Perdernales Studio. In 2007 Jake released "Feelin' Good Again". The album was recorded in Austin, TX, and it was produced by Jake and bassist Mike Sconce. He enlisted drummer Alvino Bennett (Chaka Khan, Stevie Wonder, Sheena Easton, Dave Mason) and Michael Ramos (John Mellencamp, Los Lonley Boys) on keys.