Myra Melford is a jazz pianist and composer. In recent years, Melford has begun playing the harmonium as well as piano.

Melford grew up in the Chicago area. Based in New York City since the mid 80s, Melford has played as a side-person with Henry Threadgill, and has led her own bands including players such as trumpeters Dave Douglas and Cuong Vu, reed players Marty Ehrlich and Chris Speed, bassists Lindsey Horner and Stomu Takeishi, drummers Michael Sarin and Kenny Wolleson, and cellist Erik Friedlander.

In addition she has played in a leaderless trio called Equal Interest which includes Joseph Jarman of the Art Ensemble of Chicago and AACM violinist Leroy Jenkins, and has played in duos with Marty Ehrlich, Dutch percussionist Han Bennink and flutist Marion Brandis.

She is currently teaching at University of California, Berkeley.